Erin Taylor

Expertise

Biochemistry, Enzyme Kinetics, DNA Repair 

Dr. Erin Taylor grew up on the shore of Lake Michigan in Grand Haven, Michigan. Her love of science grew from participating in Science Olympiad competitions. She attended Otterbein College, a small liberal arts college in Ohio, and majored in biochemistry and molecular biology. She loved her experiences at Otterbein, so Southwestern feels like home. She continued in biochemistry at the University of Michigan, completing her doctorate in 2015. In 2016, she moved with her husband, 2 cats and a dog, down to Texas to start a postdoc at the University of Texas at Austin. She has always been interested in teaching and mentoring undergraduates and was lucky to get a fellowship at UT that allowed her to teach at Southwestern for one semester. She got hired full time at Southwestern the next year and is really excited to start her first real faculty position! In the past year she also had her first baby so she is learning how to be a new mom as well as a professor.

  • Dr. Erin Taylor grew up on the shore of Lake Michigan in Grand Haven, Michigan. Her love of science grew from participating in Science Olympiad competitions. She attended Otterbein College, a small liberal arts college in Ohio, and majored in biochemistry and molecular biology. She loved her experiences at Otterbein, so Southwestern feels like home. She continued in biochemistry at the University of Michigan, completing her doctorate in 2015. In 2016, she moved with her husband, 2 cats and a dog, down to Texas to start a postdoc at the University of Texas at Austin. She has always been interested in teaching and mentoring undergraduates and was lucky to get a fellowship at UT that allowed her to teach at Southwestern for one semester. She got hired full time at Southwestern the next year and is really excited to start her first real faculty position! In the past year she also had her first baby so she is learning how to be a new mom as well as a professor.

  • Dr. Taylor specializes in studying enzymes that interact with DNA. Her graduate research focused on the DNA repair enzyme, AlkA. AlkA is a glycosylase that searches for damaged nucleobases (A, T, G, C), in the genome of E. coli, and removes the damaged base as part of the base excision repair pathway. She uses in vitro enzyme kinetics assays to probe the mechanism of AlkA and determine its substrate specificity and rates of repair. 

    As a junior faculty member, Dr. Taylor plans on continuing this work in the soil bacterium, Bacillus subtilis, which has evolved multiple enzymes to combat DNA damage. Various molecular cloning, in vivo growth assays, protein purification and in vitro kinetics assays will be done to determine the mechanisms of DNA repair proteins in Bacillus

    Dr. Taylor also specializes in teaching enzyme kinetics to undergraduates and graduate biochemistry majors. As part of her postdoc, she became expert in computer simulation for analyzing enzyme kinetics data and will use these techniques in her classroom and laboratory.

  • Taylor, E. L., Kesavan, P. M., Wolfe, A. E., and O’Brien, P. J. (2018) Distinguishing specific and nonspecific complexes of alkyladenine DNA glycosylase, Biochemistry, (submitted).

     

    Taylor, E. L., and O’Brien, P. J. (2015) Kinetic mechanism for the flipping and excision of 1,N6-ethenoadenine by AlkA, Biochemistry 54, 898-908.

     

    Good, P. D., Kendall A., Ignatz-Hoover, J., Miller, E. L., Pai, D. A., Rivera, S. R., Carrick B., and Engelke, D. R. (2013) Silencing near tRNA genes is nucleosome-mediated and distinct from boundary element function. Gene 526, 7-15.

     

    Pratt-Hyatt, M., Pai, D. A., Haeusler, R. A., Wozniak, G. G., Good, P. D., Miller, E. L., McLeod, I. X., Yates, J. R. 3rd, Hopper, A. K., and Engelke, D. R. (2013) Mod5 protein binds to tRNA gene complexes and affects local transcriptional silencing. PNAS 110, E3081-9.

     

    Bartholomew, S. R., Bell, E. H., Summerfield, T., Newman, L. C., Miller, E. L., Patterson, B., Niday, Z. P., Ackerman, W. E. 4th, and Tansey, J. T.  (2012) Distinct cellular pools of perilipin 5 point to roles in lipid trafficking. Biochim Biophys Acta 1821, 268-278.

  • Aug 19, 2018   

    American Chemical Society National Meeting, Boston, MA

    “Teaching principles of chemical equilibria using computer simulation methods”


    Dec 4, 2015 and June 27, 2017

    Otterbein University, Westerville, OH

    Southwestern University, Georgetown, TX

    “Mechanistic studies of alkylation repair glycosylases”


    Mar 28, 2014, May 18, 2014, Aug 22, 2014, Jan 5, 2015                   

    UM Chemistry Biology Interface Training Program Symposium, University of Michigan, Ann Arbor, MI

    Annual Midwest DNA Repair Meeting, Wayne State University, Detroit, MI

    UM Biological Chemistry Departmental Retreat, Battle Creek, MI

    Enzyme Mechanisms Conference, San Luis Resort, Galveston, TX

    “Kinetic mechanism for the flipping and excision of 1,N6-ethenoadenine by AlkA”