Southwestern University > Chemistry > Rawji

• The general focus of my research is on transition metal complexes with potential as medicinal (theropeutic and diagnostic) agents. The current research involves synthesis and characterization of complexes of platinum, palladium, and ruthenium capable of interacting with DNA by intercalation as well as covalent modification, and an investigation their mode of binding.

Recent publications

• K. H. Thompson, B. D. Liboiron, Y. Sun, K. D. D. Bellman, I. A. Setyawati, B. O. Patrick, V. J. Karunaratne, G. Rawji, J. Wheeler, K. Sutton, S. Bhanot, C. Cassidy, J. H. McNeill, V. G. Yuen, C. Orvig; "Preparation & characterization of vanadyl complexes with bidentate  maltol-type ligands; in vivo comparisons of anti-diabetic therapeutic potential", J. Biol. Inorg. Chem. (2003) 8, 66.
• B. Song, K. Saatchi, G. H. Rawji, & C. Orvig; "Sythesis & solution studies of complexes of pyrone analogue ligands with vanadium(IV) and vanadium(V)", Inorg. Chim. Acta, 339 (2002) 393.
• G. H. Rawji, M. Yamada, N. P. Sadler, & R. M. Milburn, "Cobalt(III)-promoted hydrolysis of 4-nitrophenyl-phosphate: the role of dinuclear species", Inorg. Chim. Acta, 303 (2000) 168.

Student presentations (since 2001)

“Interaction of Ruthenium complexes of Schiff base ligands with DNA”, M. Z. Foote, B. Kumar & G. Rawji; 231 st Meeting of the American Chemical Society, Atlanta , Georgia . (March 2006).

“ The synthesis and characterization of a Ru(III) complex and its interaction with DNA: An interdisciplinary, project-based bioinorganic chemistry laboratory experiment”, M. Z. Foote, C. M. Maypole, B. Kumar, & G. Rawji; 230 th Meeting of the American Chemical Society, Washington, D.C. (August 2005).

“Synthesis & characterization of mixed ligand complexes of Ru(II) with DNA binding properties”; B. Kumar & G. Rawji; 229 th National Meeting of the American Chemical Society, San Diego , California (March 2005).

“DNA binding studies of [Ru(sal-phen)Cl 2 ] ”; C. Maypole, M. Zewail-Foote & G. Rawji; 229 th National Meeting of the American Chemical Society, San Diego, California (March 2005).

"Metal binding studies of lanthanide complexes of selected 12- and 13-membered bis(amide) macrocycles"; K. Ward, C. Maypole, & G. Rawji; 225 th National Meeting of the American Chemical Society, New Orleans, Lousiana (March 2003).

"Metal binding studies of lanthanide complexes of selected 12- and 13-membered bis(amide) macrocycles"; K. Ward, C. Maypole & G. Rawji; Poster presentations at 225th National Meeting of the American Chemical Society, New Orleans, Lousiana (March 2003).

“Metal binding studies of Gd(III) complexes of EDTA- and DTPA-derived bis(amide) macrocycles”; K. Ward, C. Maypole & G. Rawji; Poster presentation at 17th Undergraduate Research Symposium at University of Texas Medical Branch at Galveston, TX (February 2003).

“Binding Studies of lanthanide complexes of macrocyclic polyaminocarboxylate ligands: The effect of introduction of bulky groups on the macrocyclic ligand"; C. Maypole, K. Ward & G. Rawji; The 54th Southeast Regional Meeting, Charleston , SC (November 2002).

“Template Synthesis & Characterization of Cobalt(III) Complexes of Oxoaza-crown Macrocylclic Ligands”; S. Grimault, J. Hayes & G. Rawji; Poster presentation at The 57th Southwest Regional Meeting, San Antonio, TX (October 2001).

"Metal binding studies of bis(amide) macrocyclic ligands with selected lanthanides"; C. Maypole, K. Ward, & G. H. Rawji; The 54th Southeast Regional Meeting of the American Chemical Society, Charleston, SC. (November 2002)

"Template synthesis & characterization of cobalt(III) complexes of oxoaza-crown macrocylic ligands"; Soizic Grimault, Jason Hayes, & Gulnar Rawji; The 57th Southwest Regional Meeting of the American Chemical Society, San Antonio, TX. (October 2001)

Names of undergraduate coauthors or presenters in bold & italics.