Chemistry & Biochemistry

Kerry Bruns

Professor of Chemistry

Areas of expertise
Protein chemistry, enzymology, peptide synthesis, and study of signal transduction in cellular proliferation and differentiation

Primary teaching responsibilities are General Chemistry and Biochemistry courses

Education

PhD, New Mexico State University 1987
BA, Western New Mexico University 1981

Positions

Professor of Chemistry and Biochemistry
Southwestern University
August 01, 2005 - present

Associate Professor
Southwestern University
August 01, 1999 - July 01, 2005

Assisstant Professor
Southwestern University
August 01, 1993 - July 01, 1999

Assistant Professor
New Mexico State University Carlsbad
August 01, 1991 - July 01, 1993

Courses: Spring 2014

General Biochemistry II
Advanced Topics: Biochemistry
Methods in Lab Research

Research

Doray, Balraj, K. Bruns, P. Ghosh, and S. Kornfeld (2002) Autoinhibition of the Ligand-binding Site for GGA1/3 VHS Domains by an Internal Acidic Cluster-dileucine Motif. Proc. Natl. Acad. Sci., USA 99, 8072-8077

 

Doray, Balraj, K. Bruns, P. Ghosh, and S. Kornfeld (2002) Interaction of the Cation-dependent Mannose 6-Phosphate Receptor with GGA Proteins. J. Biol. Chem. 277, 18477-18482

 

Althouse, G., K. Bruns, L. Evans, and W. Hsu (1995) A Simple Technique for the Purification of Plasma Membranes from Ejaculated Boar Spermatozoa. Preparative Biochemistry 25, 69-80

 

Davis, T., L. Tabatabai, K. Bruns, R. Hamilton, and M. Nilsen-Hamilton (1991) Basic Fibroblast Growth Factor Induces 3T3 Fibroblasts to Synthesize and Secrete a Cyclophilin-Like Protein and beta-2 Microglobulin.  Biochim et Biophys. Acta  1095, 145-152

 

Hamilton, R., K. Bruns, M. Delgado, J. Shim, Y. Fang, D. Denhardt, and M. Nilsen- Hamilton (1991) Developmental Expression of Cathepsin L and c-rasHa in the Mouse Placenta. Mol. Reprod. Devel. 30, 285-292

 

Nilsen-Hamilton, M., Y. Jang, M. Delgado, J. Shim, K. Bruns, C. Chiang, Y. Fang, C. Parfett, D. Denhardt, and R.  Hamilton (1991) Regulation of the Expression of Mitogen-Regulated Protein (MRP; Proliferin) and Cathepsin L in Cultured Cells and in the Murine Placenta.  Mol. Cell. Endocrinol. 77, 115-121

 

Bruns, K. and E. R. Casillas (1990) Partial Purification and Characterization of an Acetylcarnitine Hydrolase from Bovine Epididymal Spermatozoa.  Arch. Biochem Biophys.  227, 1-7

 

Bruns, K. and E. R. Casillas (1989) The Metabolism of Acetylcarnitine and Acetate By Bovine and Hamster Epididymal Spermatozoa. Biol. Reprod. 41, 218-226


Seminars & Presentations

Carlos P. Cardenas and Kerry Bruns "Inhibition of gene expression by using an anthrapyrazole/peptide nucleic acid conjugate" 239th American Chemical Society National Meeting in San Francisco, CA,  March, 2010

Elizabeth Ferrick and  Kerry Bruns "Cathepsin L overexpression in Kirsten sarcoma virus-transformed fibroblasts may be epigenetically controlled by histone H3 acetylation" 239th American Chemical Society National Meeting in San Francisco, CA, March, 2010

 

James M. Bradley, Frank Guziec. and Kerry Bruns "Synthesis and characterization of peptide nucleic acid for experimental use of directing anthrapyrazole intercalation"  Undergraduate Research Poster Sessions at the 233rd ACS national meeting, Chicago, IL, March 25-29, 2007.

 

Asher Begleiter, Naweed Raza, Christine M. Pickering, Marsha K. Leith, Lynn J. Guziec, Christopher N. Prichard, Kerry A. Bruns, Frank S. Guziec Jr., "Studies with Novel Sulfur-Oxide Alkylating Agents" American Association for Cancer Research, April 2006

 

Michael Brinkman, Michael Henzl, and Kerry A. Bruns  "Binding Studies of Calmodulin and Peptide Ligands Related to HIV I-gp-160"  presented at the 227th American Chemical Society National Meeting, Anaheim, CA, April 2004


Hatley, Jade, Kerry Bruns, and Emily Niemeyer "Detection of Tetracycline Antibiotics and Tetracycline-resistant Genes in Surface Water and Topsoil Surrounding Livestock Operations" presented at the 227th American Chemical Society National Meeting, Anaheim, CA, April 2004

 

Jessica Ables, Michael Henzl, and Kerry A. Bruns "Binding Studies of Calmodulin and Peptide Ligands Related to HIV II Coat Glycoprotein", Annual Meeting of the American Society for Biochemistry and Molecular Biology, San Diego, CA,  April 15, 2003

 

Doray, Balraj, K. Bruns, and S. Kornfeld  "Interaction of GGA2 with the Cation-dependent Mannose 6-Phosphate Receptor" 41st Annual Meeting of the American Society for Cell Biology,Washington, DC, December 9, 2001

 

Kimberly Sanford and Kerry Bruns "Identification and Cellular Localization of Lectin-binding Proteins in Mouse Spleen and Cultured Human Lymphocytes", Texas Academy of Science Annual Meeting, Texas A&M University at Kingsville, March 10, 2000

 

Adrianne Cones and Kerry Bruns "Identifying Amino Acid Sequences of Peptides that Bind to Pokeweed Mitogen; Structural Similarity Between Peptide and Carbohydrate Ligands", Society for Advancement of Chicanos and Native Americans National Conference, Portland, OR, Oct. 7-10, 1999

 

Christopher Prichard: "Design and Preparation of Novel Anticancer Mustard Derivatives" Dr. Frank Guziec and Dr. Kerry Bruns, advisors.  Alpha Chi Regional Convention, San Antonio, TX.  February 27, 1998

 

Rajendra Bhati: "Identification of Peptide Ligands for the Calcium-Calmodulin Complex by the Method of Phage Display"  Dr. Kerry Bruns, advisor.  Alpha Chi Regional Convention, San Antonio, TX. February 27, 1998


Groups & Affiliations

American Society for Biochemistry and Molecular Biology

American Chemical Society

American Association for the Advancement of Science

American Society for Cell Biology

Sigma Xi Scientific Research Society

Texas Association for Advisors of the Health Professions

Council on Undergraduate Research


Interests

Gardening, Photography, Woodworking