Southwestern

Engaging Minds, Transforming Lives

Biology

Faculty

Maria Cuevas

Maria Cuevas, Assistant Professor of Biology, Paideia Professor 2008-2011

 

EDUCATION/TRAINING

POST-DOCTORAL TRAINING, Clinical Chemistry, Loyola University Medical Center, Maywood, IL

Ph.D., BIOLOGY, Concentration Reproductive Endocrinology, Boston University, Boston, MA

MS, BIOMEDICAL ENGINEERING, Concentration Physiology, Northwestern University, Evanston, IL

BS, BIOLOGY, Purdue University, W. Lafayette, IN

 

TEACHING AND RESEARCH STATEMENTS

I am a strong believer that students will benefit the most when they are actively involved in learning.  In addition, I think that the teacher¹s enthusiasm for the topic sparks their interest and motivation. My experience suggests that students get really excited and engaged when they see the direct correlation between the learned concepts and the every day application. My goal is to equip the students with skills that will be essential in their careers including writing, presentation skills (understanding/organizing/delivery of information) and teamwork to mention a few.

My research interests lie primarily in three areas, reproductive endocrinology, cellular steroid biosynthetic pathways, and hormonal regulation of fuel metabolism. As a scientist I believe in a multi-technique approach. I, therefore, have used tissue culture, radioimmuoassays, steroid receptor binding analysis and the biochemical analysis of steroidogenesis and steroid metabolism to answer the scientific questions at hand.

Courses Taught: Organ Physiology, Endocrinology, Human Biology (non-science course), Comparative Vertebrate Morphology, Introduction to Research, Methods in Cellular and Molecular Biology, and Biology of Reproduction

 

REPRESENTATIVE PUBLICATIONS

* = undergraduate author

Cuevas, M.E. and Seilheimer, K.*  2008. In vitro cytotoxic activity of anthrapyrazole analogues in human prosate (DU-145) and testicular (NETRA-2) carcinoma cells. Oncology Reports 20:239-244.

Cuevas, M.E., Collins, K. and Callard, G.V. 1993. Stage-related changes in steroid converting enzyme activities in Squalus testis: Synthesis of biologically active metabolites via 3b-Hydroxysteroid dehydrogenase/isomerase (3 b -HSD) and 5a-reductase. Steroids 58:87-94.

Cuevas, M.E., Miller, W. and Callard, G.V. 1992. Sulfoconjugation of steroids and the vascular pathway communication in dogfish testis. J. Exp. Zool. 264:119-129.

Cuevas, M.E. and Callard, G.V. 1992. In vitro steroid secretion by staged-spermatocysts (Sertoli/germ cell units) of dogfish (Squalus acanthias) testis. Gen. Comp. Endo. 88:151-165.

Cuevas, M.E. and Callard, G.V. 1992. Androgen and progesterone receptors in shark (Squalus) testis: characteristics and stage-related distribution. Endocrinology 130(4):2173-2182.

 

RECENT ABSTRACTS AND PRESENTATIONS

*Denotes collaborative research with undergraduate:

Todd MC, Cuevas ME, Piana B* and Sheller RL. April 2009.  Overexpression of claudin-3 tight junction protein in MCF-7 and MDA-MB-415 breast cancer cell lines. American Association for Cancer Research, Denver, CO.

*Seilheimer KC, Guziec FS and Cuevas ME. 2007 Cytotoxicity of anthrapyrazoles (AP-10 and AP-11) on human prostate cancer (DU-145) and testicular cancer (NETRA-2) in culture. Texas Academy of Science: Baylor University, Waco, TX

*Seilheimer KC, *Boet C, Guziec FS and Cuevas ME. 2007 Cytotoxicity of anthrapyrazoles in various reproductive cancer cell lines. AAAS National Meeting, San Francisco, CA

*Navaira E and Cuevas ME.  2007. In vitro effects of 4-OH tamoxifen and 17b-estradiol on the human cervical cell line HeLa. Texas Academy of Science: Baylor University, Waco, TX

*Einem T, *Boet C, Cuevas M and Foote-Zewail M 2006  Effects of 4-OH tamoxifen on HEC 1B endometrial cancer cells. AAAS National Meeting, St. Louis, MO.
*Boet C and Cuevas ME. 2006. Effect of anthrapyrazoles 10 and 11 on human endometrial and mammary adenocarcinoma cells in culture.Texas Academy of Science: Lamar University, Beaumont, TX.

CONTACT:
Biology Department
Southwestern University
P.O. Box 770
Georgetown, TX 78627